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1

Bone Morphogenetic Proteins in Bone Stimulate Osteoclasts and Osteoblasts During Bone Development

Mina Okamoto, Junko Murai, Hideki Yoshikawa, Noriyuki Tsumaki

Journal:

Journal of Bone and Mineral Research

Year:

2006

Language:

english

File:

PDF, 6.98 MB

english, 2006

2

CARTILAGE-SPECIFIC OVEREXPRESSION OF C-PROPEPTIDE OF TYPE II COLLAGEN AFFECTED MATRIX MINERALIZATION IN TRANSGENIC MICE

Matsui, Yoshito, Nakata, Ken, Adachi, Eijiro, Tsumaki, Noriyuki, Kimura, Tomoatsu, Yasui, Natsuo, Kataoka, Eiichiro, Fujita, Yoshi, Tsuboi, Hideki, Yoshikawa, Hideki

Journal:

Journal of Musculoskeletal Research

Year:

2003

Language:

english

File:

PDF, 1.02 MB

english, 2003

3

Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice

Mina Okamoto, Junko Murai, Yuuki Imai, Daisuke Ikegami, Nobuhiro Kamiya, Shigeaki Kato, Yuji Mishina, Hideki Yoshikawa, Noriyuki Tsumaki

Journal:

Journal of Bone and Mineral Research

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

4

Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts

Tadashi Sugiki, Taro Uyama, Masashi Toyoda, Hideo Morioka, Shoen Kume, Kenji Miyado, Kenji Matsumoto, Hirohisa Saito, Noriyuki Tsumaki, Yoriko Takahashi, Yoshiaki Toyama, Akihiro Umezawa

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 803 KB

english, 2007

5

A recurrent 1992delCT mutation of the type X collagen gene in a Japanese patient with Schmid metaphyseal chondrodysplasia

Yoshito Matsui, Tomoatsu Kimura, Noriyuki Tsumaki, Natsuo Yasui, Takahiro Ochi

Journal:

Journal of Human Genetics

Year:

1996

Language:

english

File:

PDF, 283 KB

english, 1996

6

A common FGFR3 mutation functions as a diagnostic marker for achondroplasia-group disorders in the Japanese population

Yoshito Matsui, Tomoatsu Kimura, Noriyuki Tsumaki, Haruhiko Nakahara, Nobuhito Araki, Natsuo Yasui, Takahiro Ochi

Journal:

Journal of Orthopaedic Science

Year:

1996

Language:

english

File:

PDF, 668 KB

english, 1996

7

Differential in situ expression of α2(XI) collagen mRNA isoforms in the developing mouse

Mizuo Sugimoto, Tomoatsu Kimura, Noriyuki Tsumaki, Yoshito Matsui, K. Nakata, Hirohisa Kawahata, Natsuo Yasui, Yukihiko Kitamura, Shintaro Nomura, Takahiro Ochi

Journal:

Cell and Tissue Research

Year:

1998

Language:

english

File:

PDF, 393 KB

english, 1998

8

Low-intensity pulsed ultrasound increases bone ingrowth into porous hydroxyapatite ceramic

Takao Iwai, Yoshifumi Harada, Koichi Imura, Sadahiro Iwabuchi, Junko Murai, Kunihiko Hiramatsu, Akira Myoui, Hideki Yoshikawa, Noriyuki Tsumaki

Journal:

Journal of Bone and Mineral Metabolism

Year:

2007

Language:

english

File:

PDF, 617 KB

english, 2007

9

Expression of dominant negative TGF-β receptors inhibits cartilage formation in conditional transgenic mice

Kunihiko Hiramatsu, Takao Iwai, Hideki Yoshikawa, Noriyuki Tsumaki

Journal:

Journal of Bone and Mineral Metabolism

Year:

2011

Language:

english

File:

PDF, 609 KB

english, 2011

10

Characteristics of fracture and related factors in patients with rheumatoid arthritis

Akihide Nampei, Jun Hashimoto, Junichiro Koyanagi, Takeshi Ono, Hideo Hashimoto, Noriyuki Tsumaki, Tetsuya Tomita, Kazuomi Sugamoto, Norihiro Nishimoto, Takahiro Ochi, Hideki Yoshikawa

Journal:

Modern Rheumatology

Year:

2008

Language:

english

File:

PDF, 199 KB

english, 2008

11

Bone Morphogenetic Protein Signals Are Required for Cartilage Formation and Differently Regulate Joint Development During Skeletogenesis

Noriyuki Tsumaki, Takanobu Nakase, Takahiro Miyaji, Masaaki Kakiuchi, Tomoatsu Kimura, Takahiro Ochi, Hideki Yoshikawa

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 11.50 MB

english, 2002

12

Induction of chondrogenic cells from dermal fibroblast culture by defined factors does not involve a pluripotent state

Hidetatsu Outani, Minoru Okada, Kunihiko Hiramatsu, Hideki Yoshikawa, Noriyuki Tsumaki

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 667 KB

english, 2011

13

The role of bone morphogenetic proteins in endochondral bone formation

Noriyuki Tsumaki, Hideki Yoshikawa

Journal:

Cytokine & Growth Factor Reviews

Year:

2005

Language:

english

File:

PDF, 164 KB

english, 2005

14

Splicing patterns of type XI collagen transcripts act as molecular markers for osteochondrogenic tumors

Yoshito Matsui, Tomoatsu Kimura, Noriyuki Tsumaki, Ken Nakata, Natsuo Yasui, Nobuhito Araki, Nobuyuki Hashimoto, Atsumasa Uchida, Takahiro Ochi

Journal:

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

15

Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development

Dai Suzuki, Atsushi Yamada, Takanori Amano, Rika Yasuhara, Ayako Kimura, Mizuho Sakahara, Noriyuki Tsumaki, Shu Takeda, Masaru Tamura, Masanori Nakamura, Naoyuki Wada, Tsutomu Nohno, Toshihiko Shirois

Journal:

Developmental Biology

Year:

2009

Language:

english

File:

PDF, 1.86 MB

english, 2009

16

Cartilage intermediate layer protein promotes lumbar disc degeneration

Seki, Shoji, Tsumaki, Noriyuki, Motomura, Hiraku, Nogami, Makiko, Kawaguchi, Yoshiharu, Hori, Takeshi, Suzuki, Kayo, Yahara, Yasuhito, Higashimoto, Mami, Oya, Takeshi, Ikegawa, Shiro, Kimura, Tomoatsu

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

17

Separable cis-Regulatory Elements That Contribute to Tissue- and Site-Specific α2(XI) Collagen Gene Expression in the Embryonic Mouse Cartilage

Noriyuki Tsumaki, Tomoatsu Kimura, Yoshito Matsui, Ken Nakata and Takahiro Ochi

Journal:

The Journal of Cell Biology

Year:

1996

Language:

english

File:

PDF, 2.89 MB

english, 1996

18

iPS cell technologies and cartilage regeneration

Tsumaki, Noriyuki, Okada, Minoru, Yamashita, Akihiro

Journal:

Year:

2015

Language:

english

File:

PDF, 561 KB

english, 2015

19

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes

Yamashita, Akihiro, Morioka, Miho, Kishi, Hiromi, Kimura, Takeshi, Yahara, Yasuhito, Okada, Minoru, Fujita, Kaori, Sawai, Hideaki, Ikegawa, Shiro, Tsumaki, Noriyuki

Journal:

Year:

2014

Language:

english

File:

PDF, 7.20 MB

english, 2014

20

Sox9 Reprogrammed Dermal Fibroblasts Undergo Hypertrophic Differentiation In Vitro and Trigger Endochondral Ossification In Vivo

Tam, Wai Long, O, Dorien F., Hiramatsu, Kunihiko, Tsumaki, Noriyuki, Luyten, Frank P., Roberts, Scott J.

Journal:

Cellular Reprogramming (Formerly "Cloning and Stem Cells")

Year:

2014

Language:

english

File:

PDF, 739 KB

english, 2014

21

Characteristics of fracture and related factors in patients with rheumatoid arthritis

Nampei, Akihide, Hashimoto, Jun, Koyanagi, Junichiro, Ono, Takeshi, Hashimoto, Hideo, Tsumaki, Noriyuki, Tomita, Tetsuya, Sugamoto, Kazuomi, Nishimoto, Norihiro, Ochi, Takahiro, Yoshikawa, Hideki

Journal:

Modern Rheumatology

Year:

2008

Language:

english

File:

PDF, 226 KB

english, 2008

22

Cyp26b1 within the growth plate regulates bone growth in juvenile mice

Minegishi, Yoshiki, Sakai, Yasuo, Yahara, Yasuhito, Akiyama, Haruhiko, Yoshikawa, Hideki, Hosokawa, Ko, Tsumaki, Noriyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 2.48 MB

english, 2014

23

Directed induction of chondrogenic cells from mouse dermal fibroblast culture

Noriyuki Tsumaki

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 2.53 MB

english, 2012

24

Cell reprogramming for skeletal dysplasia drug repositioning

Karagiannis, Peter, Tsumaki, Noriyuki

Journal:

Year:

2014

Language:

english

File:

PDF, 536 KB

english, 2014

25

Oxygen Tension Regulates Chondrocyte Differentiation and Function during Endochondral Ossification

Hirao, Makoto, Tamai, Noriyuki, Tsumaki, Noriyuki, Yoshikawa, Hideki, Myoui, Akira

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.76 MB

english, 2006

26

Generation of Scaffoldless Hyaline Cartilaginous Tissue from Human iPSCs

Yamashita, Akihiro, Morioka, Miho, Yahara, Yasuhito, Okada, Minoru, Kobayashi, Tomohito, Kuriyama, Shinichi, Matsuda, Shuichi, Tsumaki, Noriyuki

Journal:

Stem Cell Reports

Year:

2015

Language:

english

File:

PDF, 5.45 MB

english, 2015

27

Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes

Itoh, Yumi, Sanosaka, Masato, Fuchino, Hiroyuki, Yahara, Yasuhito, Kumagai, Ayako, Takemoto, Daisaku, Kagawa, Mai, Doi, Junko, Ohta, Miho, Tsumaki, Noriyuki, Kawahara, Nobuo, Takemori, Hiroshi

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 7.85 MB

english, 2015

28

Tissue engineering (IBMS/JSBMR joint meeting 2013)

Tsumaki, Noriyuki

Journal:

Year:

2013

Language:

english

File:

PDF, 99 KB

english, 2013

29

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

Nakamura, Yukio, Yamamoto, Koji, He, Xinjun, Otsuki, Bungo, Kim, Youngwoo, Murao, Hiroki, Soeda, Tsunemitsu, Tsumaki, Noriyuki, Deng, Jian Min, Zhang, Zhaoping, Behringer, Richard R., Crombrugghe, Ben

Journal:

Nature Communications

Year:

2011

Language:

english

File:

PDF, 986 KB

english, 2011

30

Role of CDMP-1 in Skeletal Morphogenesis: Promotion of Mesenchymal Cell Recruitment and Chondrocyte Differentiation

Noriyuki Tsumaki, Kazuhiro Tanaka, Eri Arikawa-Hirasawa, Takanobu Nakase, Tomoatsu Kimura, J. Terrig Thomas, Takahiro Ochi, Frank P. Luyten and Yoshihiko Yamada

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 4.71 MB

english, 1999

31

Activation of Cartilage-Derived Morphogenetic Protein-1 in Torn Rotator Cuff

Nakase, Takanobu, Sugamoto, Kazuomi, Miyamoto, Takashi, Tsumaki, Noriyuki, Luyten, Frank P., Inui, Hiroaki, Myoui, Akira, Tomita, Tetsuya, Yoshikawa, Hideki

Journal:

Clinical Orthopaedics and Related Research®

Year:

2002

Language:

english

File:

PDF, 854 KB

english, 2002

32

Smad6/Smurf1 Overexpression in Cartilage Delays Chondrocyte Hypertrophy and Causes Dwarfism with Osteopenia

Mitsuru Horiki, Takeshi Imamura, Mina Okamoto, Makoto Hayashi, Junko Murai, Akira Myoui, Takahiro Ochi, Kohei Miyazono, Hideki Yoshikawa and Noriyuki Tsumaki

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 5.05 MB

english, 2004

33

Limited Immunogenicity of Human Induced Pluripotent Stem Cell-Derived Cartilages

Kimura, Takeshi, Yamashita, Akihiro, Ozono, Keiichi, Tsumaki, Noriyuki

Journal:

Tissue Engineering Part A

Year:

2016

Language:

english

File:

PDF, 701 KB

english, 2016

34

A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain

Makino, Hiroto, Seki, Shoji, Yahara, Yasuhito, Shiozawa, Shunichi, Aikawa, Yukihiko, Motomura, Hiraku, Nogami, Makiko, Watanabe, Kenta, Sainoh, Takeshi, Ito, Hisakatsu, Tsumaki, Noriyuki, Kawaguchi, Y

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 6.46 MB

english, 2017

35

A-674563 increases chondrocyte marker expression in cultured chondrocytes by inhibiting Sox9 degradation

Kobayashi, Tomohito, Fujita, Kaori, Kamatani, Takashi, Matsuda, Shuichi, Tsumaki, Noriyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

36

Direct Induction of Chondrogenic Cells from Human Dermal Fibroblast Culture by Defined Factors

Outani, Hidetatsu, Okada, Minoru, Yamashita, Akihiro, Nakagawa, Kanako, Yoshikawa, Hideki, Tsumaki, Noriyuki, Covas, Dimas Tadeu

Journal:

Year:

2013

Language:

english

File:

PDF, 6.33 MB

english, 2013

37

Proposal of patient-specific growth plate cartilage xenograft model for FGFR3 chondrodysplasia

Kimura, Takeshi, Ozaki, Tomonori, Fujita, Kaori, Yamashita, Akihiro, Morioka, Miho, Ozono, Keiichi, Tsumaki, Noriyuki

Journal:

Osteoarthritis and Cartilage

Year:

2018

Language:

english

File:

PDF, 3.55 MB

english, 2018

38

Integration capacity of human iPS cell-derived cartilage

Chen, Xike, Yamashita, Akihiro, Morioka, Miho, Senba, Toshika, Kamatani, Takashi, Watanabe, Akira, Kosai, Azuma, Tsumaki, Noriyuki

Journal:

Tissue Engineering Part A

Year:

2018

Language:

english

File:

PDF, 4.51 MB

english, 2018

39

Considerations in hiPSC-derived cartilage for articular cartilage repair

Yamashita, Akihiro, Tamamura, Yoshihiro, Morioka, Miho, Karagiannis, Peter, Shima, Nobuyuki, Tsumaki, Noriyuki

Journal:

Inflammation and Regeneration

Year:

2018

Language:

english

File:

PDF, 2.46 MB

english, 2018

40

Changes in acetyl-CoA mediate Sik3-induced maturation of chondrocytes in endochondral bone formation

Kosai, Azuma, Horike, Nanao, Takei, Yoshiaki, Yamashita, Akihiro, Fujita, Kaori, Kamatani, Takashi, Tsumaki, Noriyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2019

Language:

english

File:

PDF, 1.64 MB

english, 2019

41

Changes in acetyl-CoA mediate Sik3-induced maturation of chondrocytes in endochondral bone formation

Kosai, Azuma, Horike, Nanao, Takei, Yoshiaki, Yamashita, Akihiro, Fujita, Kaori, Kamatani, Takashi, Tsumaki, Noriyuki

Journal:

Biochemical and Biophysical Research Communications

Year:

2019

File:

PDF, 1.64 MB

2019

42

Visualization of human iPS cells-derived 3D cartilage tissue by gelatin nanospheres

Murata, Yuki, Jo, Jun-ichiro, Yukawa, Hiroshi, Tsumaki, Noriyuki, Baba, Yoshinobu, Tabata, Yasuhiko

Journal:

Tissue Engineering Part C Methods

Year:

2020

File:

PDF, 2.66 MB

2020

43

Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage

Takei, Yoshiaki, Morioka, Miho, Yamashita, Akihiro, Kobayashi, Tomohito, Shima, Nobuyuki, Tsumaki, Noriyuki

Journal:

Scientific Reports

Year:

2020

File:

PDF, 4.53 MB

2020

44

Culture substrateâassociated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells

Yamashita, Akihiro, Yoshitomi, Hiroyuki, Kihara, Shunsuke, Toguchida, Junya, Tsumaki, Noriyuki

Journal:

Stem Cells Translational Medicine

Year:

2020

File:

PDF, 16.24 MB

2020

45

Evaluation of FGFR inhibitor ASP5878 as a drug candidate for achondroplasia

Ozaki, Tomonori, Kawamoto, Tatsuya, Iimori, Yuki, Takeshita, Nobuaki, Yamagishi, Yukiko, Nakamura, Hiroaki, Kamohara, Masazumi, Fujita, Kaori, Tanahashi, Masayuki, Tsumaki, Noriyuki

Journal:

Scientific Reports

Year:

2020

File:

PDF, 5.44 MB

2020